Interleukin-8 and neutrophil extracellular traps in children with lupus nephritis and vitamin C deficiency.
Chanunya SantiworakulWilasinee SaisornNuanpan SiripenAsada LeelahavanichkulPornpimol RianthavornPublished in: Pediatric nephrology (Berlin, Germany) (2023)
Our study demonstrated correlation among vitamin C deficiency, increased NET formation, and IL-8 upregulation in children with lupus nephritis. A prospective study is required to evaluate cause‒effect relationships of vitamin C status, NET formation and IL-8 expression. A higher resolution version of the Graphical abstract is available as Supplementary information.