Comparative complete scheme and booster effectiveness of COVID-19 vaccines in preventing SARS-CoV-2 infections with SARS-CoV-2 Omicron (BA.1) and Delta (B.1.617.2) variants: A case-case study based on electronic health records.

Irina KislayaAndré Peralta-SantosVítor BorgesLuís VieiraCarlos SousaBibiana FerreiraAna PeleritoJoão Paulo GomesPedro Pinto LeiteBaltazar Nunesnull nullAusenda MachadoAna Paula RodriguesVasco Ricoca PeixotoPedro CasacaEugenia FernandesEduardo RodriguesRita FerreiraJoana IsidroMiguel PintoSílvia DuarteDaniela SantosLuís MenesesJosé Pedro AlmeidaAna MatiasSamanta FreireTeresa Grilo

Published in: Influenza and other respiratory viruses (2023)

Consistent reduction in vaccine-induced protection against infection with Omicron was observed. Complete primary vaccination may not be protective against SARS-CoV-2 infection in regions where Omicron variant is dominant.

Keyphrases

sars cov
electronic health record
respiratory syndrome coronavirus
clinical decision support
randomized controlled trial
high glucose
systematic review
coronavirus disease
diabetic rats
copy number
adverse drug
drug induced
endothelial cells
oxidative stress
gene expression
dna methylation