Dopamine Pathway and Parkinson's Risk Variants Are Associated with Levodopa-Induced Dyskinesia.
Yuri L SoseroSara Bandres-CigaBart FerwerdaMaria T P TocinoDìaz R BellosoPilar Gomez-GilJohann FaouziPille TabaLukas PavelkaTainà M MarquesClarissa P C GomesAlexey KolodkinPatrick MayLukasz M MilanowskiZbigniew K WszolekRyan J UittiPeter HeutinkJacobus J van HiltenDavid K SimonShirley EberlyIgnacio AlvarezLynne KrohnEric YuKathryn FreemanUladzislau RudakouJennifer A RuskeyFarnaz AsayeshManuel Menéndez-GonzàlezPau PastorOwen A RossRejko Krügernull nullJean-Christophe CorvolSulev KõksPablo MirRob M A de BieHirotaka IwakiZiv Gan Ornull nullPublished in: Movement disorders : official journal of the Movement Disorder Society (2024)
This study suggests that variants implicated in PD and in the dopaminergic transmission pathway play a role in the risk/time to develop LID. Further studies will be necessary to examine how these findings can inform clinical care. © 2024 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.