MiR-27b-3p Regulation in Browning of Human Visceral Adipose Related to Central Obesity.

Jing YuYifan LvWenjuan DiJuan LiuXiaocen KongYunlu ShengMin HuangShan LvHanmei QiMei GaoHui LiangSarah KimZan FuHong ZhouGuoxian Ding

Published in: Obesity (Silver Spring, Md.) (2017)

These findings highlight the decreased browning ability of VAT from humans with obesity and the role of miR-27b-3p in regulating browning of human visceral adipocytes. They suggest that miR-27b-3p should be further explored as a potential target for the treatment of central obesity.

Keyphrases

high fat diet induced
insulin resistance
adipose tissue
metabolic syndrome
endothelial cells
weight loss
type diabetes
skeletal muscle
weight gain
induced pluripotent stem cells
pluripotent stem cells