A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells.
Moeen RiazJonas MattissonGalina PolekhinaAndrew BakshiJonatan HalvardsonMarcus DanielssonAdam AmeurJohn McNeilLars A ForsbergPaul LacazePublished in: Cell & bioscience (2021)
Our results suggest that a PRS for LOY could become a useful tool for risk prediction and targeted intervention for common disease in men.