Withdrawal reasons of randomized controlled trials on type 2 diabetes: a systematic review.

Shahrzad Mohseni Ozra Tabatabaei Malazy Maryam Peimani Hanieh-Sadat Ejtahed Mehrnoosh Khodaeian Elahe Nazeri Zahra Nouhi Kajal Khodamoradi Maryam Aboeerad Bagher Larijani

Published in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2021)

High proportion of reported discontinuation in blinded RCTs on patients with T2DM was related to drug adverse effects. Overall, the total number and reason of drop out were unsatisfactory.

Keyphrases

type diabetes
glycemic control
cardiovascular disease
insulin resistance
study protocol
drug induced
adverse drug
randomized controlled trial
placebo controlled
emergency department
metabolic syndrome
clinical trial
double blind