Advancing Myocardial Infarction Treatment: Harnessing Multi-Layered Recellularized Cardiac Patches with Fetal Myocardial Scaffolds and Acellular Amniotic Membrane.
Zahra HassannejadKiarad FendereskiSeyedeh Sima DaryabariSaman Behboodi TanourloueeMehrshad DehnaviAbdol-Mohammad KajbafzadehPublished in: Cardiovascular engineering and technology (2024)
This study suggests that multi-layered recellularized cardiac patches are a promising surgical intervention for myocardial infarction, showcasing significant potential by promoting angiogenesis, mitigating fibrosis, and minimizing scar tissue formation in MI models. These features are pivotal for enhancing the therapeutic outcomes in MI patients, focusing on the restoration of the myocardial structure and function post-infarction.
Keyphrases
- left ventricular
- end stage renal disease
- heart failure
- ejection fraction
- randomized controlled trial
- newly diagnosed
- chronic kidney disease
- prognostic factors
- endothelial cells
- peritoneal dialysis
- vascular endothelial growth factor
- reduced graphene oxide
- highly efficient
- type diabetes
- mesenchymal stem cells
- patient reported outcomes
- machine learning
- deep learning
- umbilical cord
- replacement therapy
- smoking cessation