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Comparing PCSK9 Monoclonal Antibody Treatment Strategies Following Myocardial Infarction Using Negative Control Outcomes: A Target Trial Emulation Study.

Rosa SlootAlexander BreskinLisandro D ColantonioAndrew G AllmonYing YuSwati SakhujaLigong ChenPaul MuntnerM Alan BrookhartNafeesa N Dhalwani
Published in: Epidemiology (Cambridge, Mass.) (2024)
A comparative effectiveness study of these treatments using the current approach would likely bias results due to the low number of PCSK9 mAb initiators.
Keyphrases
  • monoclonal antibody
  • clinical trial
  • heart failure
  • randomized controlled trial
  • type diabetes
  • skeletal muscle
  • phase ii
  • insulin resistance