TLR9 gene polymorphism -1486T/C (rs187084) is associated with uterine cervical neoplasm in Mexican female population.
Ana Isabel Burguete-GarcíaMargarita Bahena-RománKirvis Torres-PovedaAna I Burguete-GarcíaVicente Madrid-MarinaPublished in: Journal of cancer research and clinical oncology (2017)
Our findings indicate that genotype TT in the -1486 locus of the TLR9 gene could comprise a risk genotype for HPV infection, squamous intraepithelial cervical lesion, and uterine cervical neoplasm in Mexican female population. Further studies with larger samples are needed to evaluate if the peripheral expression of TLR9 could be used as a biomarker of uterine cervical neoplasm progression.