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Expression of brain-derived neurotrophic factor and formation of migrasome increases in the glioma cells induced by the adipokinetic hormone.

Sibel KöktürkSibel DoğanCansu Eda YılmazYeliz CetinkolOguz Mutlu
Published in: Revista da Associacao Medica Brasileira (1992) (2024)
A positive correlation was found between the brain-derived neurotrophic factor expression level and the formation of migrasome, which indicates that the increased expression of brain-derived neurotrophic factor and the number of migrasomes may be involved to metastasis of the rat C6 glioma cell line induced by the Anax imperator adipokinetic hormone. Therefore, the expression of brain-derived neurotrophic factor and migrasome formation may be promising targets for preventing tumor proliferation, invasion, and metastasis in glioma.
Keyphrases
  • poor prognosis
  • binding protein
  • long non coding rna
  • oxidative stress
  • cell migration