Exosomes From Subjects With Multiple Sclerosis Express EBV-Derived Proteins and Activate Monocyte-Derived Macrophages.
May F MradEsber S SabaLayane NakibSamia Joseph KhouryPublished in: Neurology(R) neuroimmunology & neuroinflammation (2021)
Exosomes expressing EBV proteins correlate with disease activity and induce an inflammatory response in MDMs that is compounded by the origin of the responder cells.
Keyphrases
- disease activity
- inflammatory response
- multiple sclerosis
- epstein barr virus
- systemic lupus erythematosus
- rheumatoid arthritis
- mesenchymal stem cells
- rheumatoid arthritis patients
- induced apoptosis
- ankylosing spondylitis
- diffuse large b cell lymphoma
- stem cells
- juvenile idiopathic arthritis
- cell cycle arrest
- dendritic cells
- lipopolysaccharide induced
- endothelial cells
- lps induced
- toll like receptor
- endoplasmic reticulum stress
- bone marrow