Tissue Hypoxia and Alterations in Microvascular Architecture Predict Glioblastoma Recurrence in Humans.

Andreas Stadlbauer Thomas M M KinfeIlker EyüpogluMax ZimmermannMelitta KitzwögererKlaus PodarMichael BuchfelderGertraud HeinzStefan OberndorferFranz Marhold

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)

Hypoxia may represent an early sign for GBM recurrence. This might become useful in the development of new combined diagnostic-therapeutic approaches for tailored clinical management of recurrent GBM. Further preclinical and in-human studies are required for validation and evaluation.

Keyphrases

endothelial cells
free survival
induced pluripotent stem cells
pluripotent stem cells
cell therapy
smoking cessation