Granulocyte-Monocyte Apheresis in Steroid-Dependent, Azathioprine-Intolerant/Resistant Moderate Ulcerative Colitis: A Prospective Multicenter Study.
Gianni ImperialiArnaldo AmatoMaria Maddalena TerpinIvo BeverinaAurora BortoliMassimo DevaniChiara Viganònull nullPublished in: Gastroenterology research and practice (2017)
Our study shows that a standard course of granulocyte-monocyte apheresis is associated with a 36% steroid-free clinical remission in patients with steroid-dependent, azathioprine-intolerant or resistant moderate ulcerative colitis. Apheresis might represent an alternative to biologic therapy or surgery in this specific subgroup of patients. This trial is registered with Clinicaltrial.gov NCT03189888.
Keyphrases
- ulcerative colitis
- peripheral blood
- end stage renal disease
- dendritic cells
- newly diagnosed
- ejection fraction
- chronic kidney disease
- rheumatoid arthritis
- high intensity
- minimally invasive
- endothelial cells
- clinical trial
- phase iii
- study protocol
- prognostic factors
- randomized controlled trial
- stem cells
- coronary artery bypass
- disease activity
- acute coronary syndrome
- patient reported outcomes
- phase ii
- patient reported