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Using 3D image registration to maximize the reproducibility of longitudinal bone strength assessment by HR-pQCT and finite element analysis.

R M PlettT D KempL A BurtE O BillingtonD A HanleySteven K Boyd
Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2021)
Although 3D registration cannot negate motion artifacts, it plays an important role in detecting and reducing variability in FE estimates for longitudinal HR-pQCT data and is well suited for estimating effects of interventions in in vivo longitudinal studies of bone strength.
Keyphrases
  • cross sectional
  • bone mineral density
  • finite element analysis
  • soft tissue
  • bone loss
  • deep learning
  • electronic health record
  • big data
  • magnetic resonance imaging
  • computed tomography