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AF9 sustains glycolysis in colorectal cancer via H3K9ac-mediated PCK2 and FBP1 transcription.

Xuefeng HeXinyang ZhongYi FangZijuan HuZhiyu ChenYaxian WangHuixia HuangSenlin ZhaoDawei LiPing Wei
Published in: Clinical and translational medicine (2023)
AF9 is essential for the upregulation of PCK2 and FBP1, and the disruption of the miR-145/AF9 axis may serve as a potential target for the development of CRC therapeutics.
Keyphrases
  • atrial fibrillation
  • cell proliferation
  • long non coding rna
  • poor prognosis
  • small molecule
  • transcription factor
  • long noncoding rna
  • signaling pathway