Rhodiola crenulata reduces ventricular arrhythmia through mitigating the activation of IL-17 and inhibiting the MAPK signaling pathway.
Ya-Wen HsiaoYung-Nan TsaiYu-Ting HuangShuen-Hsin LiuYenn-Jiang LinLi-Wei LoYu-Feng HuFa-Po ChungShien-Fong LinShih-Lin ChangSatoshi HigaShih-Ann ChenPublished in: Cardiovascular drugs and therapy (2020)
RC inhibited the expression of IL-17 and its downstream target genes that were mediated by activation of several MAPKs, which decreased the levels of fibrosis and apoptosis and suppressed VA.