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Expression and clinical value of programmed cell death-ligand 1 (PD-L1) in diffuse large B cell lymphoma: a retrospective study.

Li-Yang HuXiao-Lu XuHui-Lan RaoJie ChenRen-Chun LaiHui-Qiang HuangWen-Qi JiangTong-Yu LinZhong-Jun XiaQing-Qing Cai
Published in: Chinese journal of cancer (2017)
PD-L1 expression is more common in the non-GCB subtype than in the GCB subtype. PD-L1 expression in tumor microenvironment has a negative correlation with C-Myc. PD-L1 positivity predicts short survival in DLBCL patients. For patients with PD-L1 expression, more strategy such as anti-PD-L1 antibody treatment should be recommended.
Keyphrases
  • diffuse large b cell lymphoma
  • epstein barr virus
  • end stage renal disease
  • ejection fraction
  • poor prognosis
  • newly diagnosed
  • prognostic factors
  • peritoneal dialysis
  • combination therapy
  • replacement therapy