Fungal extracts stimulate solitary chemosensory cell expansion in noninvasive fungal rhinosinusitis.
Neil N PatelVasiliki TriantafillouIvy W MainaAlan D WorkmanCharles Ching Lick TongEdward Cheng-Lung KuanPeter PapagiannopoulosJohn V BossoNithin D AdappaJames N PalmerMichael A KohanskiDe'Broski R HerbertNoam A CohenPublished in: International forum of allergy & rhinology (2019)
Although fungal antigens are known to potentiate immune response through innate cytokines, including IL-25, the early expansion of SCCs in the presence of fungus has not been described. This early event in the pathogenesis of noninvasive fungal rhinosinusitis may represent a target for intervention.