Humoral and Cellular Immune Responses Against Severe Acute Respiratory Syndrome Coronavirus 2 Variants and Human Coronaviruses After Single BNT162b2 Vaccination.

Metodi V StankovAnne CossmannAgnes BonifaciusAlexandra Dopfer-JablonkaGema Morillas RamosNina GödeckeAnna Zychlinsky ScharffChristine HappleAnna-Lena BoeckAnh Thu TranIsabell PinkMarius M HoeperRainer BlasczykMartin S WinklerInga NehlmeierAmy KempfHeike Hofmann-WinklerMarkus HoffmannBritta Eiz-VesperStefan PöhlmannGeorg M N Behrens

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)

These results call into question whether neutralizing antibodies significantly contribute to protection against COVID-19 upon single vaccination and suggest that cellular immunity is central for the early defenses against COVID-19.

Keyphrases

sars cov
respiratory syndrome coronavirus
immune response
coronavirus disease
endothelial cells
copy number
dendritic cells
gene expression
pluripotent stem cells
zika virus
genome wide