GQ-11: A new PPAR agonist improves obesity-induced metabolic alterations in LDLr-/- mice.

Jacqueline C SilvaEdson M de OliveiraWalter M TuratoGustavo H G TrossiniVinícius G MaltarolloMarina G R PittaIvan R PittaBeatriz de Las HerasLisardo BoscáMartina RudnickiDulcineia S P Abdalla

Published in: International journal of obesity (2005) (2018)

GQ-11 is a partial/dual PPARα/γ agonist that demonstrates anti-diabetic effects. Additionally, it improves the lipid profile and ameliorates chronic inflammation associated with obesity in atherosclerosis-prone mice.

Keyphrases

high fat diet induced
insulin resistance
type diabetes
metabolic syndrome
adipose tissue
skeletal muscle
weight loss
oxidative stress
cardiovascular disease
weight gain
diabetic rats
high glucose
drug induced
fatty acid
physical activity
wound healing
stress induced