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High podoplanin and low E-cadherin levels correlate with better prognosis in adenoid cystic carcinoma.

Jacqueline E van der WalNicola SgaramellaLena Norberg SpaakKatarina ZborayovaKarin Nylander
Published in: Clinical and experimental dental research (2019)
Our findings show that ACCs express significantly higher levels of podoplanin compared with both MECs and PACs and that high levels are correlated to better survival. Even though the group of PACs analysed was small, these tumours, despite their tendency to perineural spread, which they have in common with ACC, differ from ACCs concerning expression of factors with a known connection to tumour spread.
Keyphrases
  • poor prognosis
  • binding protein