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The long noncoding RNA MALAT1 modulates adipose loss in cancer-associated cachexia by suppressing adipogenesis through PPAR-γ.

Jun HanLei ShenZheng ZhanYuguo LiuChang ZhangRuochen GuoYangjun LuoZhiqin XieYing FengGuohao Wu
Published in: Nutrition & metabolism (2021)
This study indicated that MALAT1 is associated with adipose loss in cancer-associated cachexia by regulating adipogenesis through PPAR-γ, which may potentially be a novel target for the diagnosis and treatment of cancer-associated cachexia in the clinic.
Keyphrases
  • long noncoding rna
  • insulin resistance
  • high fat diet induced
  • adipose tissue
  • fatty acid