The long noncoding RNA MALAT1 modulates adipose loss in cancer-associated cachexia by suppressing adipogenesis through PPAR-γ.
Jun HanLei ShenZheng ZhanYuguo LiuChang ZhangRuochen GuoYangjun LuoZhiqin XieYing FengGuohao WuPublished in: Nutrition & metabolism (2021)
This study indicated that MALAT1 is associated with adipose loss in cancer-associated cachexia by regulating adipogenesis through PPAR-γ, which may potentially be a novel target for the diagnosis and treatment of cancer-associated cachexia in the clinic.