Deletion of Jdp2 enhances Slc7a11 expression in Atoh-1 positive cerebellum granule cell progenitors in vivo.
Chia-Chen KuKenly WuputraKohsuke KatoJia-Bin PanChia-Pei LiMing-Ho TsaiMichiya NoguchiYukio NakamuraChung-Jung LiuTe-Fu ChanMing-Feng HouShigeharu WakanaYang-Chang WuChang-Shen LinDeng-Chyang WuKazunari K YokoyamaPublished in: Stem cell research & therapy (2021)
Jdp2 is a critical regulator of Slc7a11 transporter during the antioxidation response, which might control the growth, apoptosis, and differentiation of GCPs in the cerebellar lobes. These observations are consistent with our previous study in vitro.