Risk factors and prediction of hypoglycaemia using the Hypo-RESOLVE cohort: a secondary analysis of pooled data from insulin clinical trials.

Joseph C Mellor Dmitry Kuznetsov Simon R Heller Mari-Anne Gall Myriam Rosilio Stephanie A Amiel Mark Ibberson Stuart J McGurnaghan Luke A K Blackbourn William Berthon Adel Salem Yongming Qu Rory J McCrimmon Bastiaan E De Galan Ulrik Pedersen-Bjergaard Joanna Leaviss Paul M McKeigue Helen Martina Colhoun

Published in: Diabetologia (2024)

Although hypoglycaemia rates show large variation according to sociodemographic and clinical characteristics and treatment history, looking at a 6 week period of hypoglycaemia events and glucose measurements predicts future hypoglycaemia risk.

Keyphrases

type diabetes
risk factors
clinical trial
glycemic control
insulin resistance
randomized controlled trial
machine learning
combination therapy
skeletal muscle
deep learning
phase ii
smoking cessation
data analysis