[Prevalence of anabolic androgenic steroid use, its effect on the male pituitary-gonadal axis, and the possibility of reproductive rehabilitation].
Nikolai P LikhonosovAlina Yu BabenkoPublished in: Problemy endokrinologii (2019)
The purpose of this review is to assess the prevalence of AA steroid use, to identify the steroids that are used, and to present the negative effects of AA steroids on the human body while describing the mechanisms of their actions on the male reproductive system. The review highlights the diagnostic features of steroid-induced hypogonadism, and assesses the effectiveness of various drugs in the reproductive rehabilitation of patients who cease taking AA steroids. Emphasis is placed on the feasibility and effectiveness of various drug treatments in the context of post cycle therapy (PCT), which seeks to stabilize and restore normal hormonal function. All this data is necessary for the development of modern treatment algorithms for steroid-induced hypogonadism in men.
Keyphrases
- high glucose
- endothelial cells
- randomized controlled trial
- diabetic rats
- drug induced
- systematic review
- risk factors
- replacement therapy
- machine learning
- emergency department
- stem cells
- oxidative stress
- metabolic syndrome
- polycystic ovary syndrome
- bone marrow
- mesenchymal stem cells
- cell therapy
- data analysis
- insulin resistance
- adverse drug
- artificial intelligence