Cerebral artery conditional blood velocity in sickle cell disease: a multicentre study and evidence for active treatment.
Emmanuel ModebeCharles NonyeluAugustine DuruOsita EzenwosuBarth ChukwuAnazoeze MaduChinedu EzekekwuJohn AnekeMildred IzukaChisom Nri-EzediOluomachi NnachiAlozie EzeIfeoma AjubaEmeka OkwummuoJane ChilakaChinenye OnodugoUwaoma Fidelis-EwaObineche AgwuIkechukwu AnigboguEbele MuoghaluHelen OkoyeChilota EfobiObiora EjioforNgozi UgwuCollins MadukaNneka IloanusiAngela UgwuChide OkochaThomas UlasiIheanyi OkpalaPublished in: Archives of disease in childhood (2023)
Since conditional blood velocity in cerebral arteries can progress to high values and predispose to stroke, the proportion of children with SCD who are affected (15.5%) raises the question of whether regular monitoring and proactive intervention ought to be the standard of care.