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Structural hierarchy of autism spectrum disorder symptoms: an integrative framework.

Hyunsik KimCara M KeiferCraig Rodriguez-SeijasNicholas R EatonMatthew D LernerKenneth D Gadow
Published in: Journal of child psychology and psychiatry, and allied disciplines (2017)
This is the first study to examine an underlying structural hierarchy of ASD symptomatology using the bass-ackwards method. This hierarchy demonstrates how core features of ASD relate at differing levels of resolution, providing a model for conceptualizing ASD heterogeneity and a structure for integrating divergent theories of cognitive processes and behavioral features that define the disorder. These findings suggest that a more coherent and complete understanding of the structure of ASD symptoms may be reflected in a metastructure rather than at one level of resolution.
Keyphrases
  • autism spectrum disorder
  • attention deficit hyperactivity disorder
  • intellectual disability
  • sleep quality
  • single cell
  • depressive symptoms
  • working memory