Effect of phospholipid curcumin Meriva on liver histology and kidney disease in nonalcoholic steatohepatitis: A randomized, double-blind, placebo-controlled trial.

Giovanni MussoSilvia PinachFilippo MarianoFrancesca SabaFranco De MichieliLuciana FramarinMara BerruttiElena PaschettaRenato ParenteYanina Lizet CastilloNicola LeoneFrancesca CastellinoMaurizio CassaderRoberto Gambino

Published in: Hepatology (Baltimore, Md.) (2024)

In patients with NASH, Meriva administration for 72 weeks was safe, well-tolerated, and improved liver histology, possibly through NF-kB inhibition, kidney disease, and metabolic profile.

Keyphrases

double blind
placebo controlled
clinical trial
signaling pathway
lps induced
oxidative stress
fatty acid
pi k akt
phase ii
immune response
inflammatory response
open label