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Assessing Myf5 and Lbx1 contribution to carapace development by reproducing their turtle-specific signatures in mouse embryos.

Triin TekkoAnastasiia LozovskaAna NóvoaMoisés Mallo
Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2022)
Turtle-like Myf5 activity might generate a plastic state in developing trunk somites under which they can either enter carapace morphogenetic routes, possibly triggered by signals from the carapacial ridge, or still engage in the development of a standard tetrapod ribcage in the absence of those signals. In addition, trunk Lbx1 expression might play a later role in the formation of the lateral border of the carapace.
Keyphrases
  • poor prognosis
  • minimally invasive
  • genome wide
  • gene expression