Prognostic significance of melanogenesis pathway and its association with the ultrastructural characterisation of melanosomes in uveal melanoma.
Jayanti JhaMithalesh Kumar SinghLata SinghNeelam PushkerRachna MeelNeiwete LomiSameer BakhshiTapas Chandra NagKunzang ChosdolSeema SenRachna MeelPublished in: The British journal of ophthalmology (2023)
Our results demonstrated that ultrastructural changes in melanosomes and high expression of TYRP2, MITF and SILV could dysregulate the melanogenesis pathway and might be responsible for the aggressive behaviour of UM.