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Molecular surveillance of the Pfmdr1 N86Y allele among Congolese pregnant women with asymptomatic malaria.

Louis Regis Dossou-YovoFrancine NtoumiFelix Koukouikila-KoussoundaJeannhey Christevy VouvounguiAyodele AdedojaDavid NderuThirumalaisamy P VelavanArsène Lenga
Published in: Malaria journal (2020)
This study gives an update on the prevalence of Pfmdr1 N86Y alleles in Brazzaville, Republic of Congo. It also raises concern on the imminent emergence of resistance against artemether-lumefantrine in this setting. This study underscores the importance to regular artemether-lumefantrine efficacy monitoring to inform the malaria control programme of the Republic of Congo.
Keyphrases
  • plasmodium falciparum
  • pregnant women
  • risk factors
  • randomized controlled trial
  • clinical trial
  • single molecule