The Correlation between YAP and RhoA Expression in Prostate and Ovarian Tumor Stroma.

Published in: Asian Pacific journal of cancer prevention : APJCP (2022)

We found that YAP was overexpressed in prostate and ovarian cancer stroma. Furthermore, the correlation between RhoA and YAP expression suggested that RhoA-YAP signals could physiologically be involved in tumor stroma. Thus, targeting RhoA-YAP may be an intriguing avenue for cancer therapeutics in neoplastic epithelial cells as well as tumor stroma.

Keyphrases

prostate cancer
poor prognosis
benign prostatic hyperplasia
binding protein
small molecule
cancer therapy
long non coding rna