Association between osteocalcin and residual β-cell function in children and adolescents newly diagnosed with type 1 diabetes: a pivotal study.

M ValenziseFortunato LombardoF LombardoStefano PassanisiC LombardoC LugaràF D'AmicoL GrassoM AguennouzA CatalanoGiuseppina Salzano

Published in: Journal of endocrinological investigation (2024)

Our data showed a positive correlation between OC levels and residual β-cell function in children and adolescents at T1D presentation. Further longitudinal studies evaluating OC levels in pediatric subjects with T1D are needed to better understand the complex interaction between bone and glucose metabolisms.

Keyphrases

newly diagnosed
electronic health record
cross sectional
type diabetes
blood pressure
case report
metabolic syndrome
adipose tissue
case control
insulin resistance
young adults
weight loss
bone regeneration
glycemic control