Investigation of Leukocyte Telomere Length and Genetic Variants in Chromosome 5p15.33 as Prognostic Markers in Lung Cancer.
Linda KachuriJens HelbyStig Egil BojesenDavid Chistopher ChristianiLi SuXifeng WuAdonina TardónGuillermo Fernandez-TardónJohn K FieldMichael P A DaviesChu ChenGary E GoodmanFrances A ShepherdNatasha B LeighlMing-Sound TsaoYonathan BrhaneM Catherine BrownKevin BoydDaniel ShepshelovichLei SunChristopher Ian AmosGeoffrey LiuRayjean J HungPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2020)
This is the largest lung cancer study of leukocyte TL and OS, and the first to examine the impact of the timing of TL measurement. Our findings suggest that extremely short telomeres are indicative of poor prognosis in NSCLC.