Survival and safety after neoadjuvant chemotherapy or upfront surgery for locally advanced colon cancer: meta-analysis.
Daniel AlisedaJorge Arredondo ChavesCarlos Sánchez-JusticiaAlicia AlvarellosJavier RodríguezIgnacio MatosFernando Rotellar SastreJorge BaixauliCarlos PastorPublished in: The British journal of surgery (2024)
Neoadjuvant chemotherapy is associated with a reduced hazard of recurrence and death, as well as improved overall survival and disease-free survival rates, compared with upfront surgery in patients with locally advanced colon cancer.
Keyphrases
- neoadjuvant chemotherapy
- free survival
- locally advanced
- minimally invasive
- rectal cancer
- coronary artery bypass
- systematic review
- lymph node
- sentinel lymph node
- squamous cell carcinoma
- radiation therapy
- phase ii study
- surgical site infection
- meta analyses
- randomized controlled trial
- coronary artery disease
- early stage
- percutaneous coronary intervention