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Effect of dolutegravir on folate, vitamin B12 and mean corpuscular volume levels among children and adolescents with HIV: a sub-study of the ODYSSEY randomized controlled trial.

Linda Namutebi Barlow-MoshaGrace Miriam AhimbisibweElizabeth ChappellPauline Mary AmugeAnnet NanduuduElizabeth KaudhaTimothy AmukeleDavid BalamusaniBosco KafufuAudrey NimwesigaHajira KataikeRosemary NamwanjeGladys KasangakiAlice MulindwaGerald Agaba MuzorahDickson BbuyeVictor MusiimeEmmanuel MujyambereMark SsenyongaDisan MulimaRaymonds Crespo KyambaddeJosephine NamusanjeRichard IsabiryeMariam NabalambaBarbara Musoke NakiryaCissy KityoAdeodata R KekitiinwaCarlo GiaquintoAndrew CoppDiana M GibbDeborah FordPhilippa MusokeAnna Turkovanull null
Published in: Journal of the International AIDS Society (2023)
Plasma and RBC folate levels were higher in children and adolescents receiving dolutegravir-based ART than on other ART regimens. Further studies are needed to clarify the mechanisms of these interactions and the clinical implications of increased blood folate levels.
Keyphrases
  • antiretroviral therapy
  • hiv infected
  • randomized controlled trial
  • hiv positive
  • human immunodeficiency virus
  • hiv infected patients
  • hiv aids
  • south africa