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Therapeutic Efficacy and Safety of Osteoinductive Factors and Cellular Therapies for Long Bone Fractures and Non-Unions: A Meta-Analysis and Systematic Review.

Angelos KaspirisArgyris C HadjimichaelElias S VasiliadisDionysios J PapachristouPeter V GiannoudisElias C Panagiotopoulos
Published in: Journal of clinical medicine (2022)
Administration of BMP-2 and -7, PRP and MSCs were considered effective and safe methods in fracture treatment, increasing bone consolidation, reducing time to repair and being linked to satisfactory postoperative functional scores.
Keyphrases
  • systematic review
  • bone regeneration
  • mesenchymal stem cells
  • bone mineral density
  • meta analyses
  • soft tissue
  • bone loss
  • patients undergoing
  • randomized controlled trial
  • umbilical cord