Identification of RALA as a Therapeutic Target and Prognostic Predictor of Osteosarcoma.

Gentao Fan Yan Zhu Hao ZhuLingfeng YuZhen WangChenjun ZhaiGuangxin Zhou Jianning Zhao Yi Cun Wang

Published in: BioMed research international (2023)

We identified RALA as an oncogene in OS, and RALA upregulation in a concerted manner with ABCE1 was significantly associated with worse outcomes of OS patients. Targeting RALA may prove to be a novel target for OS immunotherapy in future clinical practice.

Keyphrases

end stage renal disease
clinical practice
chronic kidney disease
ejection fraction
newly diagnosed
peritoneal dialysis
poor prognosis
cell proliferation
current status
metabolic syndrome
skeletal muscle
insulin resistance
patient reported
bioinformatics analysis
glycemic control