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Early childhood neurodevelopmental outcome after open prenatal spina bifida aperta repair.

Zehra S HeppVerena M HaasBeatrice LatalMartin MeuliUeli MöhrlenSonja M SchauerRobert SteinfeldBeth A PaddenDavid A Wille
Published in: Developmental medicine and child neurology (2021)
Children with non-trial open prenatal SBA repair show favourable cognitive outcome in the low-average range at 1 and 2 years of age. While gross motor function remained delayed, fine motor function was age appropriate. The correlation between Griffiths and Bayley-III allows a prediction about neurodevelopmental outcome at the age of 1 year. What this paper adds Children with non-trial open prenatal spina bifida repair show favourable cognitive outcome. Gross motor function remains impaired, while fine motor function is age appropriate. At 2 years of age, 50.8% of children were walking. Neurodevelopmental testing correlated between 1 (Griffiths Mental Developmental Scales) and 2 (Bayley Scales of Infant and Toddler Development, Third Edition) years.
Keyphrases
  • young adults
  • pregnant women
  • minimally invasive
  • study protocol
  • air pollution
  • mental health
  • randomized controlled trial