Keap1/Nrf2 Signaling Pathway.
Gerasimos P SykiotisPublished in: Antioxidants (Basel, Switzerland) (2021)
Nuclear factor, erythroid 2-like transcription factor 2 (Nrf2) and its cytoplasmic inhibitor, kelch-like ECH-associated protein 1 (Keap1), comprise a redox-responsive endogenous antioxidant defense module that orchestrates the expression of cytoprotective genes to maintain homeostasis [...].
Keyphrases
- nuclear factor
- oxidative stress
- transcription factor
- toll like receptor
- signaling pathway
- poor prognosis
- protein protein
- genome wide identification
- induced apoptosis
- genome wide
- pi k akt
- epithelial mesenchymal transition
- anti inflammatory
- dna binding
- binding protein
- immune response
- gene expression
- innate immune
- cell proliferation
- drug delivery
- genome wide analysis