Low-Dose Coconut Oil Supplementation Induces Hypothalamic Inflammation, Behavioral Dysfunction, and Metabolic Damage in Healthy Mice.
Alana Carolina Costa VerasTamires Dos SantosIsis de Cássia Alves MartinsCamilla Mendes de SouzaCamila Libardi AmaralBeatriz da Silva FrancoAlessandro Spencer de Souza HolandaAndrea Maculano EstevesMarciane MilanskiAdriana Souza TorsoniLeticia Martins Ignacio-SouzaMarcio Alberto TorsoniPublished in: Molecular nutrition & food research (2021)
These results show that a low-dose CO changes the behavioral pattern, induces inflammatory pathway activation, TLR4 expression in healthy mice, and stimulates the pro-inflammatory response through a TLR4-mediated mechanism.