Login / Signup

Baseline and Longitudinal Neutrophil-to-Lymphocyte Ratio as Prognostic Factor for Metastatic Colorectal Cancer: A Secondary Analysis of the ITACa Randomized Trial.

Elisabetta PetracciAlessandro PassardiAnnibale BiggeriMartina ValgiustiManlio MontiGiovanni Luca FrassinetiOriana NanniEmanuela Scarpi
Published in: JCO precision oncology (2024)
In our study, inflammatory indexes collected longitudinally showed a significant adverse prognostic role, thus suggesting the collection and use of such data for better clinical decision making. In the specific setting, we considered this is particularly important as the treatment effect seemed to be modified by both the baseline and longitudinal inflammation statuses. However, further research is needed to understand the possible factors underlying these results.
Keyphrases
  • prognostic factors
  • metastatic colorectal cancer
  • oxidative stress
  • cross sectional
  • electronic health record
  • big data
  • adverse drug
  • data analysis
  • drug induced