The effect of doxycycline on neuron-specific enolase in patients with traumatic brain injury: a randomized controlled trial.

Noha O MansourMohamed A ShamaRehab H Werida

Published in: Therapeutic advances in chronic disease (2021)

Adjunctive early use of doxycycline might be a novel option that halts the ongoing secondary brain injury in patients with moderate to severe TBI. Future larger clinical trials are warranted to confirm these findings.

Keyphrases

brain injury
traumatic brain injury
clinical trial
subarachnoid hemorrhage
cerebral ischemia
severe traumatic brain injury
current status
high intensity
early onset
phase ii
randomized controlled trial
open label
double blind