Transcriptomic Profiling of Electroacupuncture Regulating the Molecular Network in Hippocampus of Rats with Cerebral Ischemia-Reperfusion Injury.
Jiang PanHong-Wei ShenKai-Lin YangCheng ChenWen-Ying ShiBi-Dan LouSai-Qun LiJin-Wen GeWei ZhangPublished in: Evidence-based complementary and alternative medicine : eCAM (2022)
Electroacupuncture intervention on hand-taiyin meridian may reduce neurological function scores, inhibit neuron apoptosis, and enhance neuronal repair neuroreparation in MCAO/R rats, which may be related to the regulation of genes such as Caspase 9, BDNF, Grin2a, and PlexinD1.
Keyphrases
- cerebral ischemia
- subarachnoid hemorrhage
- ischemia reperfusion injury
- oxidative stress
- cell death
- brain injury
- blood brain barrier
- single cell
- randomized controlled trial
- neuropathic pain
- cell cycle arrest
- rna seq
- cognitive impairment
- gene expression
- spinal cord injury
- genome wide identification
- cerebral blood flow