Functionally-instructed modifiers of response to ATR inhibition in experimental glioma.

Bianca WalterSophie HirschLaurence KuhlburgerAaron StahlLeonard SchnabelSilas WisserLara A HaeusserFoteini TsiamiSarah PlögerNarges AghaallaeiAdvaita M DickJulia SkokowaChristian SchmeesMarkus TemplinKatja Schenke-LaylandMarcos TatagibaSven NahnsenDaniel J MerkGhazaleh Tabatabai

Published in: Journal of experimental & clinical cancer research : CR (2024)

In conclusion, our study leads to the identification of novel combination therapies involving ATRi that could inform future preclinical studies and early phase clinical trials.

Keyphrases

clinical trial
stem cells
randomized controlled trial
current status
dna damage response
open label
phase iii