Protector Role of Cx30.2 in Pancreatic β-Cell against Glucotoxicity-Induced Apoptosis.

Ortega-Cuellar Daniel Ignacio González-Sánchez Gabriela Piñón-Zárate Marco A Cerbón Victor De la RosaYuliana Franco-JuárezAndrés Eliú Castell-Rodríguez Leon D Islas Cristina Coronel-Cruz

Published in: Biology (2024)

The data suggest that the upregulation of Cx30.2 protects β cells from hyperglycemia-induced apoptosis. Furthermore, Cx30.2 may be a promising avenue of therapeutic investigation for the treatment of glucose metabolic disorders.

Keyphrases

induced apoptosis
signaling pathway
endoplasmic reticulum stress
oxidative stress
single cell
electronic health record
cell proliferation
cell therapy
poor prognosis
blood glucose
combination therapy
machine learning
long non coding rna
data analysis