Identification of Key Genes and FUNCTIONAL Pathway in Radioresistance of Non-Small Cell Lung Cancer.

Shouying LiJiaxin FengHaiyan WengFeng ZhaoGuohui CuiWenkui FuXiaorong LinHai Hu

Published in: Cancer management and research (2022)

Although immune system activation occurs followed by radiation resistance, we hypothesized that the upregulation of PD-L1 expression caused by STAT1 activation might be one of the mechanisms of radiotherapy resistance.

Keyphrases

cell proliferation
bioinformatics analysis
radiation induced
poor prognosis
radiation therapy
signaling pathway
locally advanced
squamous cell carcinoma
cancer stem cells