Radiotherapy dose escalation using pre-treatment diffusion-weighted imaging in locally advanced rectal cancer: a planning study.

Nathan HearnAlexandria LeppienPatrick O'ConnorKatelyn CahillDaisy AtwellDinesh VignarajahMyo Min

Published in: BJR open (2023)

This is the first study to evaluate the feasibility of DWI-targeted upfront radiotherapy boost in LARC. This work will inform an upcoming clinical feasibility study.

Keyphrases

locally advanced
rectal cancer
diffusion weighted imaging
neoadjuvant chemotherapy
squamous cell carcinoma
early stage
radiation therapy
clinical trial
randomized controlled trial
magnetic resonance
radiation induced
computed tomography
drug delivery
contrast enhanced
diffusion weighted
replacement therapy