Der p 1-specific regulatory T-cell response during house dust mite allergen immunotherapy.
Tadech BoonpiyathadMilena SokolowskaHideaki MoritaBeate RückertJeannette I KastMarcin WawrzyniakAtik SangasapaviliyaPanitan PradubpongsaRattanaporn FuengthongPattarawat ThantiworasitSunee SirivichayakulWilliam Wai-Hung KwokKiat RuxrungthamMübeccel AkdişCezmi A AkdisPublished in: Allergy (2019)
The results indicate that AIT involves upregulation of the activated allergen-specific Treg cells and downregulation of dysfunctional allergen-specific Treg cell subset. Correction of dysregulated Treg cells responses during AIT is associated with improved clinical response.