Der p 1-specific regulatory T-cell response during house dust mite allergen immunotherapy.

Tadech BoonpiyathadMilena SokolowskaHideaki MoritaBeate RückertJeannette I KastMarcin WawrzyniakAtik SangasapaviliyaPanitan PradubpongsaRattanaporn FuengthongPattarawat ThantiworasitSunee SirivichayakulWilliam Wai-Hung KwokKiat RuxrungthamMübeccel AkdişCezmi A Akdis

Published in: Allergy (2019)

The results indicate that AIT involves upregulation of the activated allergen-specific Treg cells and downregulation of dysfunctional allergen-specific Treg cell subset. Correction of dysregulated Treg cells responses during AIT is associated with improved clinical response.

Keyphrases

induced apoptosis
cell cycle arrest
allergic rhinitis
cell proliferation
endoplasmic reticulum stress
oxidative stress
transcription factor
poor prognosis
cell death
stem cells
risk assessment
bone marrow
human health
drinking water
health risk assessment