Bivalent mRNA vaccine effectiveness against SARS-CoV-2 variants of concern.
Monika KumariShih-Chieh SuKang-Hao LiangHsiu-Ting LinYu-Feng LuKai-Chi ChenWan-Yu ChenHan-Chung WuPublished in: Journal of biomedical science (2023)
Our results show that combining two mRNA sequences may be an effective way to develop a broadly protective SARS-CoV-2 vaccine against a wide range of variant types. Importantly, we provide the optimal combination regimen and propose a strategy that may prove useful in combating future VOCs.